Recommended Regimens
- Azithromycin 1 g orally in a single dose
OR - Doxycycline 100 mg orally twice a day for 7 days
Alternative Regimens
- Erythromycin base 500 mg orally four times a day for 7 days
OR - Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days
OR - Levofloxacin 500 mg orally once daily for 7 days
OR - Ofloxacin 300 mg orally twice a day for 7 days
- Organism: Obligate intracellular, gram negative bacerium, chalymdia trachomatis
- Epidemiology:
- It is the most common bacterial cause of STDs and the most commonly reported STD with 1.8 million cases in 2018, representing a 19% increase since 2014 (CDC)
- Symptoms/Findings: Majority are asymptomatic
- Cervicitis
- Urethritis
- Urinary frequency
- Dysuria
- Pelvic Inflammatory Disease (PID)
- Vaginal discharge
- Fitz-Hugh-Curtis syndrome – peritoneal inflammation, and perihepatitis
- Epididymitis
- Prostatitis
- Proctitis
- Conjunctivitis
- Pharyngitis
- Testing:
- In women, the sensitivity of nucleic acid amplification testing (NAAT) on urine (92%) appears to be slightly lower than the sensitivity on vaginal samples (97%). Self-taken vulvovaginal swabs are as accurate as clinician-performed tests. In men, the diagnostic test of choice is NAAT of first-catch urine, with urethral swab as a secondary option. NAAT can also be performed on conjunctival swabs.
Source