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Push Dose Phenylephrine

Mixing

  • Draw 1 ml (10mg) from a phenylephrine 10 mg/ ml vial
  • Inject into 100 cc bag of saline
  • Shake thoroughly, then draw 10cc from the bag into an empty syringe.
  • Label syringe. Now each 1 ml contains 100 mcg of phenylephrine

Dosing

  • 0.5-2 ml (50-200 mcg) every 2-5 minutes PRN hypotension
  • Duration 10-20 minutes
  • Onset < 1 minute

Pharmacology

Alpha agonist. Increases blood pressure without increasing heart rate. Can be used to improve coronary perfusion but will increase cardiac afterload.

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