Mixing
- Draw 1 ml (10mg) from a phenylephrine 10 mg/ ml vial
- Inject into 100 cc bag of saline
- Shake thoroughly, then draw 10cc from the bag into an empty syringe.
- Label syringe. Now each 1 ml contains 100 mcg of phenylephrine
Dosing
- 0.5-2 ml (50-200 mcg) every 2-5 minutes PRN hypotension
- Duration 10-20 minutes
- Onset < 1 minute
Pharmacology
Alpha agonist. Increases blood pressure without increasing heart rate. Can be used to improve coronary perfusion but will increase cardiac afterload.